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Tuesday, Jul 15th
10:00 AM – 12:00 PM
EDT
Tech Session I: Nanomedicine and Nanoscale Delivery (Focus: Gene)
Nanomedicine and Nanoscale Delivery
Gene Delivery and Gene Editing
Tuesday, Jul 15th
10:54 AM – 11:05 AM
EDT
Overcoming Chemoresistance in Colorectal Cancer by FcRn-Driven Nucleic Acid Delivery
Oral Abstract Speaker:
Natália Teixeira, n/a
– Instituto de Investigação e Inovação em Saúde (i3S)
Nanomedicine and Nanoscale Delivery
Gene Delivery and Gene Editing
Tuesday, Jul 15th
2:00 PM – 4:00 PM
EDT
Tech Session II: Gene Delivery and Gene Editing I
Gene Delivery and Gene Editing
Sponsored By
Tuesday, Jul 15th
2:04 PM – 2:29 PM
EDT
Nature-inspired nanotechnology for RNA delivery to myeloid cells and bone marrow progenitors
Invited Speaker - Exceptional Abstract:
Roy van der Meel, PhD
– Eindhoven University of Technology
Gene Delivery and Gene Editing
Tuesday, Jul 15th
2:29 PM – 2:54 PM
EDT
Development of SORT lipid nanoparticles (LNPs) for genome correction of disease-causing mutations
Invited Speaker - Exceptional Abstract:
Daniel J. Siegwart, Ph.D.
– University of Texas Southwestern Medical Center
Gene Delivery and Gene Editing
Tuesday, Jul 15th
2:54 PM – 3:05 PM
EDT
Cardiac-tropic Lipid Nanoparticles Provide Selective Vascularization After Myocardial Infarction
Oral Abstract Speaker:
Junchao Xu, n/a
– university of pennsylvania
Gene Delivery and Gene Editing
Tuesday, Jul 15th
3:05 PM – 3:16 PM
EDT
Targeting NEBL via a siRNA-loaded nanocarrier for advanced non-small cell lung cancer treatment
Oral Abstract Speaker:
Bei Zhang, n/a
– University of Pittsburgh
Gene Delivery and Gene Editing
Tuesday, Jul 15th
3:16 PM – 3:27 PM
EDT
One-component Janus dendrimers: a novel platform for efficient mRNA vaccine delivery
Oral Abstract Speaker:
Wook-Jin Park, Ph.D
– University of Pennsylvania
Gene Delivery and Gene Editing
Tuesday, Jul 15th
3:27 PM – 3:38 PM
EDT
RNA Nanotherapeutics with Fibrosis Overexpression and Retention for MASH Treatment
Oral Abstract Speaker:
Xinzhu -. shan, PhD (she/her/hers)
– Peking University
Gene Delivery and Gene Editing
Tuesday, Jul 15th
3:38 PM – 3:49 PM
EDT
Virus-Mimicking Nanoparticles for Precise Intracellular siRNA Delivery
Oral Abstract Speaker:
Tong Wu, n/a
– Shanghai Institute of Materia Medica, Chinese Academy of Sciences, China
Gene Delivery and Gene Editing
Tuesday, Jul 15th
3:49 PM – 4:00 PM
EDT
Unraveling endosomal escape: mechanistic insights into lipid nanoparticle-mediated RNA delivery
Local Chapter Speaker:
Alice Spadea, n/a
– MPI-CBG
Gene Delivery and Gene Editing
Wednesday, Jul 16th
10:00 AM – 12:00 PM
EDT
Tech Session III: Gene Delivery and Gene Editing II
Gene Delivery and Gene Editing
Wednesday, Jul 16th
10:04 AM – 10:29 AM
EDT
Enhanced pDNA Delivery Mediated by Backbone-Degradable RAFT Copolymers
Invited Speaker - Exceptional Abstract:
Adam J. Gormley, PhD
– Rutgers University
Gene Delivery and Gene Editing
Wednesday, Jul 16th
10:29 AM – 10:54 AM
EDT
DNA-loaded lipid nanoparticles (DNA-LNPs): a platform technology to treat common chronic diseases
Invited Speaker - Exceptional Abstract:
Jacob Brenner, MD, PhD
– University of Pennsylvania
Gene Delivery and Gene Editing
Wednesday, Jul 16th
10:54 AM – 11:05 AM
EDT
Therapeutic Genome Editing of Gliomas via Focused Ultrasound-Mediated Ribonucleoprotein Delivery
Oral Abstract Speaker:
Anna C. Debski, BS
– University of Virginia
Gene Delivery and Gene Editing
Wednesday, Jul 16th
11:05 AM – 11:16 AM
EDT
Lipid Nanoparticle Delivery for CRISPR Gene Editing in Primary Human T-cells
Oral Abstract Speaker:
Joy J. Chen, BS
– UC Berkeley
Gene Delivery and Gene Editing
Wednesday, Jul 16th
11:16 AM – 11:27 AM
EDT
Breaking Barriers: Stabilized Lipid Nanoparticles Transform Oral Nucleic Acid Delivery
Oral Abstract Speaker:
Kanika Suri, PhD
– Takeda Pharmaceuticals, Northeastern University
Gene Delivery and Gene Editing
Wednesday, Jul 16th
11:27 AM – 11:38 AM
EDT
The lipid nanoparticle shape and morphology affect the efficiency and duration of mRNA transfection
Oral Abstract Speaker:
Sara Elsafy, MSc
– RWTH Aachen University
Gene Delivery and Gene Editing
Wednesday, Jul 16th
11:38 AM – 11:49 AM
EDT
Optimization of Nanoparticle Delivery of Nucleic Acids to Cells using Poly(glycerol esters)
Oral Abstract Speaker:
Brian P. Ginn, Ph.D.
– Secant Group, LLC.
Gene Delivery and Gene Editing
Wednesday, Jul 16th
11:49 AM – 12:00 PM
EDT
Optimized lipid nanoparticles for CRISPR/Cas9 delivery: advancing gene editing in lung tumor cells
Oral Abstract Speaker:
Simone Carneiro, PhD
– Ludwig-Maximilians-University of Munich
Gene Delivery and Gene Editing
Wednesday, Jul 16th
2:00 PM – 4:00 PM
EDT
Tech Session IV: Nanomedicine and Nanoscale Delivery (Focus: Gene)
Nanomedicine and Nanoscale Delivery
Gene Delivery and Gene Editing
Wednesday, Jul 16th
2:04 PM – 2:29 PM
EDT
Peptide-Lipid Conjugates for Enhancing mRNA-LNP Delivery and Colon Cancer Vaccines
Invited Speaker - Exceptional Abstract:
Kuo-Ching Mei, n/a
– Binghamton University-SUNY
Nanomedicine and Nanoscale Delivery
Gene Delivery and Gene Editing
Wednesday, Jul 16th
2:29 PM – 2:54 PM
EDT
Polymeric Mesoscale Nanoparticles Selectively Target Gene Therapies to the Kidneys
Invited Speaker - Exceptional Abstract:
Ryan M. Williams, PhD
– The City College of New York
Nanomedicine and Nanoscale Delivery
Gene Delivery and Gene Editing
Wednesday, Jul 16th
2:54 PM – 3:05 PM
EDT
Novel Biodegradable Lipids for the Delivery of mRNA to Liver and Genome Editing in Lung Epithelia
Oral Abstract Speaker:
Manan Rajith Singh, n/a
– Massachusetts Institute of Technology
Nanomedicine and Nanoscale Delivery
Gene Delivery and Gene Editing
Wednesday, Jul 16th
3:05 PM – 3:16 PM
EDT
Lipid stereochemistry of lipid nanoparticles significantly influences mRNA expression levels in vivo
Oral Abstract Speaker:
Renzo Knol, n/a
– Leiden University
Nanomedicine and Nanoscale Delivery
Gene Delivery and Gene Editing
Wednesday, Jul 16th
3:16 PM – 3:27 PM
EDT
Lipid-siRNA Organization Modulates the Intracellular Dynamics of Lipid Nanoparticles
Oral Abstract Speaker:
Yulin Mo, n/a
– University of Toronto
Nanomedicine and Nanoscale Delivery
Gene Delivery and Gene Editing
Wednesday, Jul 16th
3:27 PM – 3:38 PM
EDT
Dual Centrifugation: A Novel Perspective on LNP Formulation Development
Oral Abstract Speaker:
Valentin Bender, n/a
– University of Freiburg
Nanomedicine and Nanoscale Delivery
Gene Delivery and Gene Editing
Wednesday, Jul 16th
3:38 PM – 3:49 PM
EDT
Precision Attack: GD2-Directed siRNA-Lipid Nanoparticles to Target Neuroblastoma’s Weak Spots
Oral Abstract Speaker:
Amy Logan, PhD (she/her/hers)
– Children's Cancer Institute Australia
Nanomedicine and Nanoscale Delivery
Gene Delivery and Gene Editing
Wednesday, Jul 16th
3:49 PM – 4:00 PM
EDT
Targeting the lower regions of the lung; a novel platform for pulmonary mRNA delivery
Oral Abstract Speaker:
Rachel Sun, n/a
– Environmental and Occupational Health Sciences Institute, Rutgers University
Nanomedicine and Nanoscale Delivery
Gene Delivery and Gene Editing
Thursday, Jul 17th
10:00 AM – 12:00 PM
EDT
Tech Session V: Gene Delivery and Gene Editing III
Gene Delivery and Gene Editing
Thursday, Jul 17th
10:04 AM – 10:29 AM
EDT
Evaluating the effects of PEGylated lipid shedding on targeted nanomedicines
Invited Speaker - Exceptional Abstract:
Lisa Volpatti, PhD
– Northwestern University
Gene Delivery and Gene Editing
Thursday, Jul 17th
10:29 AM – 10:54 AM
EDT
Engineer Lipid Nanoparticle Surface Hydrophobicity to Modulate Nano-Bio Interface and Enable Tissue-Selective mRNA Delivery
Invited Speaker - Exceptional Abstract:
Fan Zhang, PhD
– University of Florida
Gene Delivery and Gene Editing
Thursday, Jul 17th
10:54 AM – 11:05 AM
EDT
PBAE-Based Pulmonary siRNA Delivery to T-Cells: A Potential Approach for Asthma Therapy
Oral Abstract Speaker:
An Ny Nguyen, n/a
– LMU
Gene Delivery and Gene Editing
Thursday, Jul 17th
11:05 AM – 11:16 AM
EDT
Lipid nanoparticle-mediated metabolic reprogramming of dendritic cells for mRNA vaccines
Oral Abstract Speaker:
Dongyoon Kim, Ph.D.
– University of Pennsylvania
Gene Delivery and Gene Editing
Thursday, Jul 17th
11:16 AM – 11:27 AM
EDT
Advancing T cell therapy: mRNA nanocarriers optimization for ex vivo and in vivo T cell engineering
Oral Abstract Speaker:
Elisa Battistini, n/a
– University of Santiago de Compostela
Gene Delivery and Gene Editing
Thursday, Jul 17th
11:27 AM – 11:38 AM
EDT
Enhancing mRNA-lipid nanoparticle prediction via the language model and multi-task learning
Oral Abstract Speaker:
YIYANG WU, ME
– University of Macau
Gene Delivery and Gene Editing
Thursday, Jul 17th
11:38 AM – 11:49 AM
EDT
Microrobot-Assisted Delivery of Circular RNA-Lipid Nanoparticles to Treat Lung-Associated Diseases
Oral Abstract Speaker:
Bianca M. Santana, n/a
– University of Colorado Boulder
Gene Delivery and Gene Editing
Thursday, Jul 17th
11:49 AM – 12:00 PM
EDT
Multi-stage mixing creates high-efficiency core-then-shell DNA lipid nanoparticles
Oral Abstract Speaker:
Jia Nong, n/a
– University of Pennsylvania
Gene Delivery and Gene Editing
Thursday, Jul 17th
4:30 PM – 6:30 PM
EDT
Tech Session VI: Nanomedicine and Nanoscale Delivery (Focus: Gene)
Nanomedicine and Nanoscale Delivery
Gene Delivery and Gene Editing
Thursday, Jul 17th
4:34 PM – 4:59 PM
EDT
Rational design of mRNA folding architecture to enhance protein production
Invited Speaker - Exceptional Abstract:
Qianqian Ni, n/a
– National University of Singapore
Nanomedicine and Nanoscale Delivery
Gene Delivery and Gene Editing
Thursday, Jul 17th
4:59 PM – 5:24 PM
EDT
mRNA Vaccine Delivery Using Lipid Nanoparticles: Focus on Muscle Cell Involvement
Invited Speaker - Exceptional Abstract:
Giovanna Lollo, PhD
– University of Lyon 1
Nanomedicine and Nanoscale Delivery
Gene Delivery and Gene Editing
Thursday, Jul 17th
5:24 PM – 5:35 PM
EDT
Hybrid polymer-lipid nanoparticles as innovative transfection vectors for microRNA delivery
Oral Abstract Speaker:
Martina Coletto (she/her/hers)
– Politecnico di Torino
Nanomedicine and Nanoscale Delivery
Gene Delivery and Gene Editing
Thursday, Jul 17th
5:35 PM – 5:46 PM
EDT
Efficient Cartilage-Targeted Gene Editing via Lipid Nanoparticles for Osteoarthritis Treatment
Oral Abstract Speaker:
muye zhou, PhD
– University of Toronto
Nanomedicine and Nanoscale Delivery
Gene Delivery and Gene Editing
Thursday, Jul 17th
5:46 PM – 5:57 PM
EDT
Dual-Shielding Approach for TNFα Silencing in Inflammatory Bowel Disease via Bioadhesive Microbeads
Oral Abstract Speaker:
Valentina Marotti, Master’s Degree in Chemistry and Pharmaceutical Techniques
– Université catholique de Louvain
Nanomedicine and Nanoscale Delivery
Gene Delivery and Gene Editing
Thursday, Jul 17th
5:57 PM – 6:08 PM
EDT
Dual Zn2+/Cu2+ Chelation-Engineered Nanotherapeutics for DNA-Mitochondrial Disruption in TNBC
Oral Abstract Speaker:
Kai Xiao, n/a
– Sichuan University
Nanomedicine and Nanoscale Delivery
Gene Delivery and Gene Editing
Thursday, Jul 17th
6:08 PM – 6:19 PM
EDT
High-throughput screening of lipid nanoparticles for lung delivery of mRNA
Oral Abstract Speaker:
Marco Túllio Alves, n/a (he/him/his)
– Federal University of Minas Gerais
Nanomedicine and Nanoscale Delivery
Gene Delivery and Gene Editing
Thursday, Jul 17th
6:19 PM – 6:30 PM
EDT
Rational macromolecular design reveals principles of ribonucleoprotein delivery for gene editing
Oral Abstract Speaker:
Ning Wang, n/a
– Memorial Sloan Kettering Cancer Center
Nanomedicine and Nanoscale Delivery
Gene Delivery and Gene Editing
Friday, Jul 18th
8:00 AM – 10:00 AM
EDT
Tech Session VII: Gene Delivery and Gene Editing IV
Gene Delivery and Gene Editing
Friday, Jul 18th
8:04 AM – 8:29 AM
EDT
Invited Speaker Presentation I
Invited Speaker:
Dan Peer (he/him/his)
– Tel Aviv University
Gene Delivery and Gene Editing
Friday, Jul 18th
8:29 AM – 8:54 AM
EDT
Invited Speaker Presentation II
Invited Speaker:
Yvonne Perrie, PhD
– University of Strathclyde
Gene Delivery and Gene Editing
Friday, Jul 18th
8:54 AM – 9:05 AM
EDT
Polymer lipids reduce anti-PEG antibody binding for repeated administration of mRNA therapeutics
Oral Abstract Speaker:
Yufen Xiao
– UT Southwestern Medical Center
Gene Delivery and Gene Editing
Friday, Jul 18th
9:05 AM – 9:16 AM
EDT
Degradable cyclic amino alcohol ionizable lipids as vectors for potent influenza mRNA vaccines
Oral Abstract Speaker:
Akash Gupta, n/a
– MIT
Gene Delivery and Gene Editing
Friday, Jul 18th
9:16 AM – 9:27 AM
EDT
In vivo nucleic acid targeted delivery in bone-marrow via antibody conjugated lipid nanoparticles
Oral Abstract Speaker:
Sabrina Khan, n/a
– AstraZeneca
Gene Delivery and Gene Editing
Friday, Jul 18th
9:27 AM – 9:38 AM
EDT
Boosting CAR T cells with Advanced Adjuvant Cancer Nanovaccines
Oral Abstract Speaker:
Flavia Sousa, PhD
– University of Groningen
Gene Delivery and Gene Editing
Friday, Jul 18th
9:38 AM – 9:49 AM
EDT
An Optimized Polymeric Delivery Platform for Pulmonary mRNA Vaccines
Oral Abstract Speaker:
Min Jiang, Master in Pharmacy
– Ludwig-Maximilians-Universität Münc
Gene Delivery and Gene Editing
Friday, Jul 18th
9:49 AM – 10:00 AM
EDT
Antibody-conjugated lipid nanoparticles to enhance extrahepatic nucleic acid delivery
Oral Abstract Speaker:
Sanjib Saha, PhD
– AstraZeneca Pharmaceuticals LP
Gene Delivery and Gene Editing
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