(121) Synthesis of exosome-mimicking exosomal nanoparticles using a microfluidic chip
Introduction: Lipid nanoparticles (LNPs) have gained significant attention for their applications in drug delivery and vaccines, especially in mRNA vaccines. Exosomes, which are released from cells, are emerging as natural alternatives with substantial promises for drug delivery. These vesicles, which replicate natural biological mechanisms and have lower immunogenicity than synthetic nanoparticles, play a role in cell-to-cell communication and the transport of therapeutic agents. However, obstacles like heterogeneity and problems with large-scale production continue to prevent their widespread use.
Learning Objectives:
Upon completion, participant will be able to understand the advantages and challenges of exosomes.
Upon completion, participant will be able to describe the development process of ENPs.
Upon completion, participant will be able to evaluate the therapeutic performance of ENPs.
