(145) Film Formation from Alpha-Glucan Polysaccharide Nanoparticles For Controlled Release ID: 2003914
Introduction: Polysaccharides are considered environmentally friendly materials because of their renewability, biodegradability, and biocompatibility. These properties are ideal when creating nanoparticles for delivery of bioactives. We developed methods for converting water-insoluble alpha-glucans produced using recombinant L. mesenteroides glucansucrase and sucrose into novel nanoparticles [1, 2]. Here we demonstrate that these alpha-glucan polysaccharide nanoparticles can be further developed into thin films and that nanoparticles encapsulating a fluorescent dye can form films capable of slow release.
Learning Objectives:
Understand the ability of alpha-glucan nanoparticles to form thin films.
Explain the slow-release capability of alpha-glucan polysaccharide thin films.
Evaluate the clarity of films formed on different surfaces.