Gene Delivery and Gene Editing (Focus Group - GDGE)
mRNA has received significant attention in the fields of gene therapy and vaccine development because it can serve as a multi-purpose platform. However, mRNA is inherently unstable due to decapping and deadenylation, leading to a short half-life and reduced translational activity. Therefore, in order to increase the translation efficiency of mRNA, we studied mRNA structures that minimize immunogenicity and improve stability.
Eunbin Kim, 4th-year Doctoral Student in Gene Delivery
Ph.D. Candidate
Ewha Womans University, Seoul National University
Seoul, Republic of Korea