Introduction: Autoimmune diseases currently affect 3-5% of the world’s population [1]. Although there have been great strides in treating autoimmune diseases, there is still a need for innovative therapeutics to improve treatment. Recently, microbial metabolites have gained traction for their impact on immune responses and have been implicated in autoimmune diseases [2]. However, the role of microbial metabolites in regulating T cell immunity and differentiation is largely unknown. Therefore, further investigation of microbial metabolites for treatment of autoimmune diseases is a promising approach.
Learning Objectives:
Understand the screening process for microbial metabolites.
Explain the hypothesized mechanism of action for Metabolite-X, and how it regulates T-cell immunity.
Comprehend the applications of Metabolite-X in treating autoimmune diseases.
