(281) Lyotropic liquid crystalline mesophases for restoring glutathione peroxidase after oxidative stress
Introduction: Lyotropic liquid crystalline mesophases formed by lipid self-assembly in aqueous conditions have gained substantial interest, mainly due to their potential applications in drug delivery, imaging, biocatalysis, and enzymatic reactions [1-3]. However, the ability to tune the phase behaviour of nanostructures and lipid bilayer properties is limited. Herein, we have investigated the influence of different lipids type, dispersing agents and additives on different mesostructure formations.
Learning Objectives:
Demonstrate preparation and characterization of lipid nanoparticles using SAXS and QELS techniques.
Understand the impact of nanoparticle on pathways associated with oxidative stress.
Describe the potential of lipid nanoparticles in restoring antioxidant enzyme activity.
