(314) Enhanced anti-sarcopenic activity of perindopril erbumine using ultradeformable liposomes
Introduction: Sarcopenia is a pertinent challenge in the super-aged societies causing reduced functional performance, poor quality of life and increased morbidity (1), (2). The aim of this study is to prepare perindopril erbumine-entrapped ultradeformable liposomes (PER-UDLs) with enhanced skin permeation and to investigate the anti-sarcopenic activity of optimized PER-UDLs in lipopolysaccharide (LPS)-induced muscle atrophy mouse model.
Learning Objectives:
Upon completion, participant will be able to understand the composition of ultradeformable liposomes
Upon completion, participant will be able to explain what the ultradeformable liposomes are
Upon completion, participant will be able to evaluate the anti-sarcopenic potential of PER-UDLs