Introduction: Acyclovir (AC), used against herpes simplex infections, has low oral bioavailability, which reduces its effectiveness, requires frequent doses and compromises treatment adherence. To overcome these limitations, studies focus on controlled release systems that improve bioavailability and prolong the drug's action. Gamma-Al2O3 (GA) is a promising solution. It is a highly porous aluminium oxide with a large surface area and excellent adsorption capacity, which makes it ideal for supporting medications. This study investigated the synthesis and characterization of GA from pseudoboehmite AC release
Learning Objectives:
Understand the process of drug release of acyclovir in the presence of gamma-alumina
Evaluate the in vitro drug release of acyclovir using an inorganic adsorbent.
Evaluate the effect of ageing in the pseudoboehmite synthesis.
