Nanomedicine and Nanoscale Delivery (Focus Group - NND)
UV/Vis spectroscopy is used for RNA, DNA, and protein quantification at 260-280nm. In Lipid Nanoparticles, particle scattering affects the spectrum, complicating UV quantification or requiring complicated particle disruption steps [1]. To address this bottleneck in nanomedicine development we introduce Scatter-Free Absorption (SFA) spectroscopy for accurate LNP payload without disruption or dyes. This new method requires almost no sample prep, only 2µg of material and achieves ca. 2% precision. Compared to RiboGreen, SFA offers results in seconds, ease of use, high throughput, and reliability.
Darren Andrews, PhD (he/him/his)
Chief Commercial Officer
Marama Labs
Glasnevin, Dublin, Ireland