(404) Design, Optimization and Evaluation of Tazarotene Loaded Emulgel Formulation for Treatment of Acne

Introduction: The emulgel delivery system combines the benefits of emulsions and gels, offering dual control over drug release and enhanced stability for topical use. Current acne treatments, such as ointments and creams, have drawbacks like stickiness, discomfort, and poor spreadability. This study designs and evaluates a novel tazarotene-loaded emulgel incorporating cinnamon oil for its antimicrobial and anti-inflammatory properties. The formulation enhances therapeutic efficacy, minimizes retinoid side effects, and shows superior anti-acne activity, presenting a promising alternative for acne treatment.