(409) Directed discovery of high-loading nanoaggregates enabled by drug-matched oligo-peptide excipients
Introduction: Nanoparticles can improve drug pharmacokinetics, but low loading efficiencies may limit treatment efficacy. Drug aggregation-based nanoparticles have demonstrated improved loadings of up to 90%, but few excipients facilitate efficient co-assembly.
Learning Objectives:
to know how we design peptide in order to have high loading drug