(412) Preparation and characterization of Eudragit S 100 nanoparticles

Introduction: Nanoparticle-based drug delivery systems are gaining traction for improving the efficacy and bioavailability of antiviral drugs. Tenofovir, and Dapivirine used to manage HIV infection known for its ability to inhibit key enzymes in viral replication, however therapeutic effectiveness is limited by poor solubility and bioavailability. Encapsulation in polymeric nanoparticles offers a potential solution by protecting the drug from degradation,controlling release,  enhancing targeted delivery. This study focuses on the development and characterization of polymeric nanoparticles of both drugs.