(435) Development of a Polymeric Nanofiber Device for the Prevention of Post-Surgical Secondary Cataracts
Introduction: Cataract surgery, the most common ophthalmic procedure, can lead to early complications like inflammation and pain, and long-term issues like capsular opacification, requiring YAG laser capsulotomy. This procedure carries risks, including retinal damage and elevated intraocular pressure. This study proposes a polymeric nanofiber device, integrated with an intraocular lens and crosslinked with an antifibrotic peptide (PAAP), to prevent fibrotic opacification of the lens.
Learning Objectives:
Explain the benefits of using this device over traditional methods.
Understand the process of developing a polymeric nanofiber for the prevention of secondary cataracts
Evaluate the safety and efficacy of the device in in vitro and in vivo models
