(468) In-Vitro Evaluation of Different Marketed Brands of Metformin Tablets Using Quality Control Tests
Introduction: Metformin is commonly prescribed for the treatment of type II diabetes non-insulin-dependent diabetes mellitus, acts by reducing hepatic glucose production. World Health Organization (WHO) has continuously supported the use of generic drug products, aiming to improve the overall health care system. The generic substitution can be considered when a generic product of an innovator drug contains identical amounts of the same active ingredient in the same dose, same dosage form and route of administration together with meeting standards for strength, purity, quality, and identity.
Learning Objectives:
Investigated in-vitro bioequivalence of different marketed generic metformin tablets in Saudi Arabia