(470) Effect of Hydroxypropyl Cellulose Grade on the Tablet Characteristics in Continuous Granulation

Introduction: Hydroxypropyl cellulose (HPC) is a versatile pharmaceutical excipient with important functions including binding and controlled release. Available in various molecular weights and particle sizes, proper grade selection is crucial. While HPC's effects in traditional granulation methods are well known, its impact in continuous manufacturing remains unconfirmed. This study evaluates how different HPC grades influence tablet characteristics in continuous granulation, supporting the pharmaceutical industry's shift toward consistent, high-quality continuous manufacturing processes.