(489) Impact of quantitative differences in carbomer on drug release from diclofenac sodium topical gels

Introduction: Differences in the formulation composition and/or the manufacturing process, may influence the physicochemical and structural (Q3) properties, and thereby, the performance of topical products. The aim of the current study is to assess the impact of quantitative differences in carbomer on a topical gel’s Q3 properties and performance such as in vitro drug release.