Tech Session III: Manufacturing and Process Scale-Up

Chair(s)

• 

  Stephanie Barrett, PhD (she/her/hers)

  Distinguished Scientist
  Merck & Co., Inc., New Jersey, United States

Co-Chair(s)

• 

  Stefaan De Smedt, PhD

  Director Lab General Biochemistry & Physical Pharmacy
  Department of Pharmaceutics - Ghent University - Belgium
  Gent, Belgium

Evaluation and characterization of delivery products, preparation and scale-up, Quality-by-design (QbD), Quality Control (QC), analytical technologies, additive manufacturing, continuous manufacturing, delivery devices, 3D-printing, green technologies (e.g., natural, non-modified, renewable materials).

Presentations:

• 10:04 AM - 10:29 AM EDT

  Process Matters: Manufacturing Robust Lipid Nanoparticles
  

  Invited Speaker: Marianne Ashford, PhD (she/her/hers) – AstraZeneca
• 10:29 AM - 10:54 AM EDT

  Mechanisms of PLGA Microencapsulation and Delivery of Peptides
  

  Invited Speaker: Steven P. Schwendeman, PhD – University of Michigan
• 10:54 AM - 11:05 AM EDT

  Optimizing Lyophilized Cake Appearance: Case Studies in Monoclonal Antibody Formulations
  

  Oral Abstract Speaker: Felipe M. Gonzalez-Fernandez, PhD (he/him/his) – Thermo Fisher Scientific
• 11:05 AM - 11:16 AM EDT

  Sustainable Waste Silk: Sericin-Hyaluronic Acid Conjugates for Advanced Drug Delivery
  

  Oral Abstract Speaker: Cristina Casadidio, PhD (she/her/hers) – University of Camerino
• 11:16 AM - 11:27 AM EDT

  Molecular dynamics simulations uncover drying-induced lipid nanoparticle–excipient interactions.
  

  Oral Abstract Speaker: Benjamin Winkeljann, PhD (he/him/his) – Ludwig-Maximilians-University Munich
• 11:27 AM - 11:38 AM EDT

  Spray drying siRNA-polymeric nanoparticles for dry powder pulmonary delivery.
  

  Oral Abstract Speaker: Antoni Torres Coll – Institut Químic de Sarrià (IQS)
• 11:38 AM - 11:49 AM EDT

  Effect of formulation strategy and polymer grade on hydration and dissolution of Push Pull OROS
  

  Local Chapter Speaker: Michal Smolenski, PhD (he/him/his) – Physiolution
• 11:49 AM - 12:00 PM EDT

  Effects of Polymer Morphology on PLGA degradation kinetics
  

  Oral Abstract Speaker: Jelynn B. Tatad, ScM (she/her/hers) – Brown University