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Final Program


CRS Abstract Guide

Gene Delivery and Gene Editing
Technical Session

Tech Session VII: Gene Delivery and Gene Editing IV

Friday, July 18, 2025
8:00 AM - 10:00 AM EDT
Location: 119 B

Delivery of nucleic acids (mRNA, pDNA, oligonucleotides) with nanoformulations, modulation of protein expression, genome editing, vaccination, overcoming biological limitations (e.g., endosomal escape, cellular targeting, biodistribution).

Presentations:

  • 8:04 AM - 8:29 AM EDT
    NanoGhost: A Stem Cell-Based Off-the-Shelf Nano-Delivery Platform for Targeted Drug and Gene Therapy

    Invited Speaker: Marcelle Machluf, PhD (she/her/hers) – Technion Israel Institute of Technology, Founder & Advisor NanoGhost Ltd., Israel, Osnat Bohana-Kashtan NanoGhots Ltd, Israel, Yonatan Malca NanoGhost Ltd, Israel

  • 8:29 AM - 8:54 AM EDT
    Designing Next-Gen LNPs: Tools, Challenges, and Opportunities

    Invited Speaker: Yvonne Perrie, PhD (she/her/hers) – University of Strathclyde

  • 8:54 AM - 9:05 AM EDT
    Polymer lipids reduce anti-PEG antibody binding for repeated administration of mRNA therapeutics

    Oral Abstract Speaker: Yufen Xiao, PhD – UT Southwestern Medical Center

  • 9:05 AM - 9:16 AM EDT
    Degradable cyclic amino alcohol ionizable lipids as vectors for potent influenza mRNA vaccines

    Oral Abstract Speaker: Akash Gupta, n/a – MIT

  • 9:16 AM - 9:27 AM EDT
    Antibody-conjugated lipid nanoparticles to enhance extrahepatic nucleic acid delivery

    Oral Abstract Speaker: Sanjib Saha, PhD (he/him/his) – AstraZeneca Pharmaceuticals LP

  • 9:27 AM - 9:38 AM EDT
    Boosting CAR T cells with Advanced Adjuvant Cancer Nanovaccines

    Oral Abstract Speaker: Flavia Sousa, PhD (she/her/hers) – University of Groningen

  • 9:38 AM - 9:49 AM EDT
    An Optimized Polymeric Delivery Platform for Pulmonary mRNA Vaccines

    Oral Abstract Speaker: Min Jiang, Master in Pharmacy – Ludwig-Maximilians-Universität Münc

  • 9:49 AM - 10:00 AM EDT
    In vivo nucleic acid targeted delivery in bone-marrow via antibody conjugated lipid nanoparticles

    Oral Abstract Speaker: Sabrina Khan – AstraZeneca