Introduction: Our group has been developing a new contraceptive technology using microneedle (MN) patches aimed at providing long-term contraception, improving access and continuation through self-administration, and offering a cost-effective solution suitable for global use. (1). This study aims to evaluate the in vivo release profile of MNs designed for six-month contraceptive delivery in rats and compare it with their in vitro release profile.
Learning Objectives:
At the completion of this activity, participants will know
Understand the design and fabrication of contraceptive MN patches.
Evaluate in vitro and in vivo release profiles of contraceptive MN patches.
Nicolas Kelhofer – MD candidate, School of Chemical and Biomolecular Engineering, Georgia Institute of Technology, Atlanta, GA, 30332, USA and Carle Illinois College of Medicine, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA; Avantika Dalvi – Postdoctoral researcher, Department of Pharmaceutical Sciences and the Biointerfaces Institute, University of Michigan, Ann Arbor, MI 48109, USA; Tao Zheng – PhD candidate, Department of Pharmaceutical Sciences and the Biointerfaces Institute, University of Michigan, Ann Arbor, MI 48109, USA; Steven Schwendeman – Ara G. Paul Professor of Pharmaceutical Sciences, Department of Pharmaceutical Sciences and the Biointerfaces Institute, University of Michigan, Ann Arbor, MI 48109, USA; Mark Prausnitz – Regents' Professor and Regents’ Entrepreneur, School of Chemical and Biomolecular Engineering, Georgia Institute of Technology, Atlanta, GA, 30332, USA
