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Final Program


CRS Abstract Guide

Bioengineering

Tech Session I: Bioengineering I

Isolation and Focal Treatment of Brain Aneurysms using Interfacial Fluid Trapping

Tuesday, July 15, 2025
10:54 AM - 11:05 AM EDT
Location: 119 A
Introduction: Current methods for localized intravascular treatments often use solid implants like metallic coils for aneurysm embolization or direct injections of therapeutic agents that can disperse beyond the aneurysms, causing complications (1,2). Thus, it's essential to develop a strategy to ensure precise delivery of injectable therapeutics to the disease site. We present a fluid-based approach utilizing surface tension and immiscible fluid interactions for localized treatment at brain aneurysm sites (3) (Fig. 1).

Learning Objectives:

At the completion of this activity, participants will know
  • Isolate non-mechanically brain aneurysms without the use of solid implants or adjunctive devices.
  • Leverage surface tension and immiscible fluid interactions for focused treatment at brain aneurysms.
  • Demonstrate an approach for intravascular localized treatment of cardiovascular and other diseases.
Tirosh Mekler, MSc – PhD student, Biomedical Engineering, Technion IIT; Mark Epshtein, PhD – Post Doc, University of Massachusetts Medical School; Yevgeniy Kreinin, MSc – PhD student, Technion IIT; Josué Sznitman, PhD – Dean, Professor, Biomedical Engineering, Technion IIT; Matthew Gounis, PhD – Professor, University of Massachusetts Medical School; Netanel Korin, PhD – Professor, Biomedical Engineering, Technion IIT