Industry Session
William Penny, Ph.D.
Sr System Account Manager
Waters | Wyatt Technology, United States
Light scattering techniques, are transforming the way we quantify and analyze liposome and lipid nanoparticle (LNP) therapeutics, playing a critical role in development, RNA quality assessment, and quality control. By combining multi-angle light scattering (MALS) with field-flow fractionation (FFF) or size- exclusion chromatography (SEC), this powerful approach offers high-resolution insights into key attributes such as size distribution, stability, RNA quality, and payload encapsulation. FFF-MALS allows for gentle, high-resolution separation, making it ideal for analyzing complex samples like LNPs without compromising their integrity. Additionally, dynamic light scattering (DLS) and electrophoretic light scattering (ELS) enable rapid, automatable batch measurements, allowing for screening of factors such as size and surface charge. Join us to discover the latest advancements in light scattering technology and learn how these powerful tools can accelerate pharmaceutical development and enhance your research.