Tech Forum: Innovations in Oral Delivery of New Drug Modalities

Sponsored By 

Sponsored by: Lonza Capsules & Health Ingredients

This expert-led session explores the latest advancements in oral delivery systems for emerging drug modalities, with a particular focus on peptides and other complex molecules. Three leading scientists will share innovative strategies and real-world case studies that are helping to overcome barriers in oral bioavailability. 

-Pr. Müllertz will kick-off the session with a deep dive into formulation options for peptides with lipid-based formulations, hydrophobic ion pairing (HIP), and permeation enhancers — highlighted through case studies such as exenatide and salmon calcitonin. 

- Dr. O’Shea will follow with an in-depth look at the preclinical evaluation of proof-of-concept formulations in preclinical species like rats and pigs, with a focus on advantages and limitations of different models. 

- Dr. Jannin will conclude the session by focusing on the advantages of enteric capsules to protect peptides and deliver high dose in the small intestine to favor absorption.

Presentations:

• 9:00 AM - 9:20 AM EDT

  Designing SNEDDS for Increasing Oral Absorption of Peptides
  

  Speaker: Anette Müllertz, PhD (she/her/hers) – University of Copenhagen
• 9:20 AM - 9:40 AM EDT

  Challenges and Innovations in the Preclinical Evaluation of Targeted Oral Dosage Forms
  

  Speaker: Joseph O’Shea, PhD (he/him/his) – Cork University
• 9:40 AM - 10:00 AM EDT

  Capsugel® Enprotect® Capsules: Precision Enteric Delivery Through Science and Customization
  

  Speaker: Vincent Jannin, PhD – Capsugel France SAS / Lonza