(288) Investigating the potential of Dual-drug-loaded Electrospun Nanofibers for Breast Cancer Treatment
Introduction: Breast cancer remains a life-threating disease globally (1). Quercetin (QUA) and Biochanin A (BCA) are plant-derived bioactive compounds that demonstrated anticancer properties by influencing many molecular factors and signaling pathways, including PI3K/Akt/mTOR, Wnt/β-catenin, and MAPK/ERK1 (2). However, their clinical application is hindered by poor water solubility and significant degradation issues.Therefore, a novel drug delivery system is developed that incorporates BCA and QUA into electrospun nanofibers, enhancing their therapeutic potential in breast cancer treatment
Learning Objectives:
Investigate clinical applications and future directions for electrospun nanofibers in breast cancer
Examine the real-world Challenges of nanomedicines and obstacles encountered in their implementation
Gain insights into the nanomedicine process and the optimization QbD
